Duodenal ulcer, Benign gastric ulcer, NSAID - associated duodenal or gastric ulcer and gastroduodenal erosions, Gastro-Oesophageal Reflux Disease, Zollinger-Ellison Syndrome, Prophylaxis of acid aspiration during anaesthesia, Acid related Dyspepsia

Duodenal ulcer, Benign gastric ulcer: 20mg/day 4-8 weeks. Max. daily dose 40mg. NSAID-associated duodenal or gastric ulcer and gastroduodenal erosions: 20mg once daily for 4 weeks. Gastro-Oesophageal Reflux Disease: 20mg/day 4-8 weeks. Increase to 40mg/day for 8 weeks if symptoms persist. Maintenance dose: 20mg/day. Zollinger-Ellison syndrome: Start at 60mg once daily. Usual range 20-120mg/day (above 80mg in divided doses). Prophylaxis of acid aspiration during anaesthesia: 40mgon the preceding evening then 40mg 2-6 hours prior to surgery. Acid related dyspepsia: 10-20mg/day for 2-4 weeks.