Roles played by individual amino acids in the human body
 
GLYCINE
Main Functions:
  • Part of the structure of haemoglobin.
  • Part of cytochromes, which are enzymes involved in energy production.
  • Inhibits sugar cravings.
  • One of the 3 critical glycogenic amino acids, along with serine and alanine.
  • Involved in glycogen production, which assists in glycogen metabolism.
Glycine Deficiency Seen In:
  • Chronic Fatigue Syndrome
  • Hypoglycaemia
  • Anaemia
  • Viral Infections
  • Candidiasis
 
HISTIDINE
Main Functions:
  • One of the 3 major Branched-Chain amino acids (BCAA), all of which are involved with muscle strength, endurance, and muscle stamina.
  • Muscle tissue uses Isoleucine as an energy source.
  • Required in the formation of haemoglobin.
Isoleucine Deficiency Seen In:
  • Obesity
  • Hyperinsulinemia
  • Panic Disorder
  • Chronic Fatigue Syndrome
  • Acute hunger
  • Kwashiorkor (starvation)
 
ISOLEUCINE
Main Functions:
  • One of the 3 major Branched-Chain amino acids (BCAA),
  • all of which are involved with muscle strength, endurance, and muscle stamina.
  • Muscle tissue uses Isoleucine as an energy source.
  • Required in the formation of haemoglobin.
Isoleucine Deficiency Seen In:
  • Hyperinsulinemia
  • Depression
  • Chronic Fatigue Syndrome
  • Acute hunger
  • Kwashiorkor (starvation)
  • Vitamin B-12 deficiency in pernicious anaemia
 
LEUCINE
Main Functions:
  • As one of the 3 branched-chain amino acids (the other 2 being Isoleucine and Valine), Leucine has all of the properties discussed with Isoleucine, as it pertains specifically to the branched-chain amino acid functions.
  • Potent stimulator of insulin.
  • Helps with bone healing.
  • Helps promote skin healing.
  • Modulates release of Enkephalins, which are natural pain-reducers.
Leucine Deficiency Seen In:
  • Hyperinsulinemia
  • Depression
  • Chronic Fatigue Syndrome
  • Acute hunger
  • Kwashiorkor (starvation)
  • Vitamin B-12 deficiency in pernicious anaemia
 
LYSINE
Main Functions:
  • Inhibits viral growth and, as a result, is used in the treatment of Herpes Simplex, as well as the viruses associated with Chronic Fatigue Syndrome
  • Helps form collagen, the connective tissue present in bones, ligaments, tendons, and joints.
  • Assists in the absorption of calcium.
  • Essential for children, as it is critical for bone formation.
  • Involved in hormone production.
  • Lowers serum triglyceride levels.
Lysine Deficiency Seen In:
  • Herpes
  • Epstein-Barr Virus
  • Chronic Fatigue Syndrome
  • AIDS
  • Anaemia
  • Hair loss
  • Weight loss
  • Irritability
 
METHIONINE
Main Functions:
  • Assists in breakdown of fats.
  • Precursor of the amino acids Cysteine (and Cystine) and Taurine.
  • Helps reduce blood cholesterol levels.
  • Antioxidant.
  • Assists in the removal of toxic wastes from the liver.
  • One of the sulphur-containing aminos (the others being Cysteine and the minor amino acid, Taurine). The sulphur-containing amino acids act as anti-oxidants which neutralise free radicals.
  • Helps prevent disorder of hair, skin, and nails due to sulphur and anti-oxidant activity.
  • Involved in the breakdown of Epinephrine, Histamine, and
  • Nicotinic Acid.
  • Natural chelating agent for heavy metals, such as lead and mercury.
Methionine Deficiency Seen In:
  • Chemical Exposure
  • Multiple Chemical Sensitivity (MCS)
  • Vegan Vegetarians
 
PHENYLALANINE
Main Functions:
  • Enhances mood, clarity of thought, concentration, and memory.
  • Suppresses appetite.
  • Major part of collagen formation.
  • While the L-form of all of the other amino acids is the one that is beneficial to people, the D and DL forms of Phenylalanine have been useful in treating pain.
  • DL-Phenylalanine is useful in reducing arthritic pain.
    Powerful anti-depressant.
  • Used in the treatment of Parkinson's Disease.
Phenylalanine Deficiency Seen In:
  • Depression
  • Obesity
  • Cancer
  • AIDS
  • Parkinson's Disease
 
THREONINE
Main Functions:
  • Required for formation of collagen.
  • Helps prevent fatty deposits in the liver.
  • Aids in production of antibodies.
  • Can be converted to Glycine (a neurotransmitter) in the central nervous system.
  • Acts as detoxifier.
  • Needed by the gastrointestinal tract for normal functioning.
  • Provides symptomatic relief in ALS (Amyotrophic Lateral Sclerosis, Lou Gehrig's Disease).
  • Threonine is often low in depressed patients. In that group of patients, Threonine is helpful in treating the depression
Threonine Deficiency Seen In:
  • Depression
  • AIDS
  • Muscle Spasticity
  • ALS (Amyotrophic Lateral Sclerosis)
  • Vegetarianism
  • Epilepsy
 
TRYPTOPHAN
Main Functions:
  • Effective sleep aid, due to conversion to serotonin.
  • Reduces anxiety.
  • Effective in some forms of depression.
  • Stimulates growth hormone.
  • Along with Lysine, Carnitine, and Taurine is effective
  • in lowering cholesterol levels.
  • Can be converted into niacin (Vitamin B3).
  • Lowers risk of arterial spasms.
  • The only plasma amino acid that is bound to protein
Tryptophan Deficiency Seen In:
  • Depression
  • Insomnia
  • Chronic Fatigue Syndrome
 
VALINE
Main Functions:
  • One of the 3 major Branched-Chain Amino Acids (BCAA) . . .the other 2 being leucine and isoleucine . . . all of which are involved with muscle strength, endurance, and muscle stamina.
  • Actively absorbed and used directly by muscle as an energy source.
  • Not processed by the liver before entering the blood stream.
  • Any acute physical stress (including surgery, sepsis, fever, trauma, starvation) requires higher amounts of Valine, Leucine and Isoleucine that any of the other amino acids.
  • During period of Valine deficiency, all of the other amino acids (and protein) are less well absorbed by the gastrointestinal tract.
Valine Deficiency Seen In:
  • Kwashiorkor
  • Hunger
  • Obesity
  • Neurological deficit
  • Elevated insulin levels
 
ARGININE
Main Functions:
  • Essential for normal immune system activity.
  • Necessary for wound healing.
  • Assists with regeneration of damaged liver.
  • Necessary for production and release of growth hormone
  • Increases release of insulin and glucogen. Arginine is the most potent amino acid in releasing insulin.
  • Assists in healing through collagen synthesis
  • Precursor to GABA, an important inhibitory neurotransmitter
  • Aids in wound healing
  • Decreases size of tumours.
  • Necessary for spermatogenesis.
Arginine Deficiencies Seen In:
  • AIDS
  • Immune deficiency syndromes.
  • Candidiasis
 
ALANINE
Main Functions:
  • Important source of energy for muscle.
  • The primary amino acid in sugar metabolism.
  • Boosts immune system by producing antibodies
  • Major part of connective tissue
Alanine Deficiencies Seen In:
  • Hypoglycaemia
  • Muscle breakdown
  • Fatigue
  • Viral infections
 
ASPARTIC ACID
Main Functions:
  • Aspartic Acid is interconvertible with Asparagine, and therefore the two amino acids have many functions in common.
  • Increases stamina.
  • One of the two main excitatory amino acids, the other being Glutamate (Glutamic Acid).
  • Helps protect the liver by aiding the removal of ammonia.
  • Involved in DNA and RNA metabolism.
  • Involved in immune system function by enhancing immunoglobulin production and anti- body formation.
Aspartic Acid Deficiency Seen In:
  • Calcium and magnesium deficiencies.
 
ASPARAGINE
Main Functions:
  • Asparagine is made from Aspartic Acid plus ATP (adenosine tri-phosphate).
  • One of the two main excitatory neurotransmitters. Glutamate, made from glutamic acid, is the other. Among their functions as neurotransmitters, of particular interest is the fact that Aspartic Acid and Asparagine have high concentrations in the hippocampus and the hypothalamus. The hippocampus is a part of the brain that plays the main role in short-term memory, while the hypothalamus is involved in the biology of emotion, and serves as a neurological gate between
  • the brain and the rest of the nervous system.
  • Aids in removing ammonia from the body.
  • May increase endurance and decrease fatigue.
  • Detoxifies harmful chemicals.
  • Involved in DNA synthesis.
  • Probably stimulates thymus gland.
 
CYSTEINE
Main Functions:
  • Antioxidant.
  • Protective against radiation, pollution, ultra-violet
  • light and other causes of increased free radical production.
  • Natural detoxifier.
  • Essential in growth, maintenance, and repair of skin.
  • Key ingredient in hair.
  • One of the 3 main sulphur-containing amino acids, along with Taurine and Methionine.
Cysteine Deficiency Seen In:
  • Chemical Sensitivity
  • Food Allergy
 
GLUTAMIC ACID
Main Functions:
  • One of two excitatory neurotransmitters, the other being aspartic acid/asparagine.
  • Excesses in brain tissue can cause cell damage. This is thought to be one of the mechanisms by why strokes kill brain cells; that is through the release of large amounts of Glutamic Acid.
  • Helps stop alcohol and sugar cravings.
  • Increases energy.
  • Accelerates wound healing and ulcer healing.
  • Detoxifies ammonia in the brain by forming glutamine, which can cross the blood-brain barrier, which Glutamic Acid cannot do.
  • Plays major role in DNA synthesis.
 
GLUTAMIC ACID
Main Functions:
  • One of two excitatory neurotransmitters, the other being aspartic acid/asparagine.
  • Excesses in brain tissue can cause cell damage. This is thought to be one of the mechanisms by why strokes kill brain cells; that is through the release of large amounts of Glutamic Acid.
  • Helps stop alcohol and sugar cravings.
  • Increases energy.
  • Accelerates wound healing and ulcer healing.
  • Detoxifies ammonia in the brain by forming glutamine, which can cross the blood-brain barrier, which Glutamic Acid cannot do.
  • Plays major role in DNA synthesis.
 
GLUTAMINE
Main Functions:
  • Important glycogenic amino acid, meaning that it is essential for helping to maintain normal and steady blood sugar levels.
  • Involved with muscle strength and endurance.
  • Essential to gastrointestinal function; provides energy to the small intestines. The intestines are the only organ in the body that uses Glutamine as its primary source of energy.
  • Glutamine has the highest blood concentration of all the amino acids.
  • Involved in DNA synthesis.
Glutamine Deficiency Seen In:
  • Chronic Fatigue Syndrome
  • Alcoholism
  • Anxiety and Panic Disorders
 
PROLINE
Main Functions:
  • Critical component of cartilage, and hence health of joints, tendons and ligaments.
  • Involved in keeping heart muscle strong.
  • Works in conjunction with Vitamin C in keeping skin and joints healthy.
 
SERINE
Main Functions:
  • One of the 3 most important glycogenic amino acids, the others being alanine and glycine.
  • Critical in maintaining blood sugar levels.
  • Boosts immune system by assisting in production of antibodies and immunoglobulins.
  • Myelin sheath (the fatty acid complex that surrounds the axons of nerves) is derived from serine. One variation of Serine namely Phosphotidyl Serine, a minor amino acid serves several important functions within the central nervous system, including development of the myelin sheath. Multiple Sclerosis is one of the so-called "De-myelinating Diseases."
  • Required for growth and maintenance of muscle.
Serine Deficiency Seen In:
  • Total body gamma and neutron irradiation
  • Hypoglycaemia
  • Candidiasis
 
TAURINE
Main Functions:
  • In the nervous system, stabilises cell membranes, which raises the seizure threshold, and helps treat epileptic seizures.
  • Acts as inhibitory neurotransmitter and is as potent as Glycine
  • Anti-convulsant effect is long-lasting and can be confirmed both clinically and by repeat EEG's (electroencephalograms).
  • Anti-oxidant. Slows down the aging process by neutralising free radicals.
  • Highest concentration of Taurine is in the heart.
  • Reduces risk of gall stones by combining with bile acids to make them water soluble.
  • Involved in stabilization of heart rhythm. Loss of intracellular
  • Taurine in the heart leads to arrhythmias.
  • Useful in treatment of Congestive heart Failure (CHF).
  • Strengthens neutrophils (white blood cells/part of immune
  • system) in their ability to kill bacteria.
  • Useful in brain injury
  • Decreases cholesterol levels
  • Highly concentrated in the eye.
Taurine Deficiency Seen In:
  • Parkinson's disease
  • Anxiety
  • Candida
  • AIDS
  • Cardiac insufficiency
  • Hypertension
  • Depression
  • Kidney failure
 
TYROSINE
Main Functions:
  • Effective anti-depressant for norepinephrine-deficient depressions.
  • Increases energy, improves mental clarity and concentration.
Tyrosine Deficiency Seen In:
  • Depression
  • Chronic Fatigue Syndrome
  • Gulf War Syndrome
  • Hypothyroidism
  • Parkinson's Disease
  • Drug addiction and dependency